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Question 138·Hard·Form, Structure, and Sense

Because short laboratory experiments can miss effects that accumulate over months, sleep researchers increasingly supplement them with longitudinal studies. Among the findings that have complicated the common view of weekend “catch-up” sleep as fully restorative ______ that variability in sleep timing, even when total weekly sleep duration remains constant, is associated with reduced alertness.

Which choice completes the text so that it conforms to the conventions of Standard English?