Question 45·Hard·Nonlinear Functions
In a pharmacology study, the concentration (in milligrams per liter) of a certain medication in a patient’s bloodstream hours after it is administered is modeled by
where and are positive constants and the baseline (long-term) concentration of is already present before the dose is given. Immediately after the dose is administered, the concentration is measured to be , and two hours later it is measured to be .
Which of the following equations represents this model?
For exponential models with a baseline (horizontal asymptote), first plug in to find the coefficient ; this is usually the initial amount above the baseline. Then use another time-and-value pair to set up an equation for the exponential part, subtracting the baseline so only the decaying term remains. Solve for the decay constant using natural logarithms, and finally plug and back into the model to match the answer choice. This approach is fast and avoids guesswork with the options.
Hints
Use the information at t = 0
Plug and into . What is , and how does that help you solve for ?
Isolate the part that is decaying
After you find , plug and into your new equation. Subtract the baseline from both sides so that only the exponential term is on the right.
Solve for k with logarithms
Once you reach an equation of the form , take the natural log (ln) of both sides. Use the fact that to solve for .
Match your A and k to a choice
Your work should give you a specific value for and for . Look at the answer choices and see which one uses the same coefficient in front of and the same factor multiplying in the exponent.
Desmos Guide
Plot the given data points
In Desmos, add a table or individual points for the measured concentrations: and . These represent the two times and their corresponding values.
Graph each candidate equation
Type each option into Desmos one at a time, for example:
y = 12*exp(-ln(2)*x) + 3y = 9*exp(-(ln(2)/2)*x) + 3y = 12*exp(-(ln(2)/2)*x) + 3y = 9*exp(-ln(2)*x) + 3(Useln(2)for andexp(...)for .)
Check which graph matches both data points
For each equation you graph, see whether its curve passes exactly through both plotted points and . The equation whose graph goes through both points corresponds to the correct model.
Step-by-step Explanation
Use the initial measurement to find A
The model is
At time , the concentration is mg/L, so plug in and :
Since , this becomes
so
Now the equation is
This tells you the coefficient in front of the exponential must be , not .
Use the 2-hour measurement to set up an equation for k
At time , the concentration is mg/L. Plug and into
Subtract from both sides to isolate the exponential term:
Now divide both sides by :
This equation will let you solve for .
Solve for k using natural logarithms
From the previous step, you have
Take the natural logarithm (ln) of both sides:
Recall that , so
Divide both sides by to solve for :
So the exponent in the model is .
Write the final model and match it to the choices
Substitute and back into the model
This gives
Comparing with the answer choices, this equation matches choice C.