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Question 4·200 Super-Hard SAT Reading Questions·Standard English Conventions

Ordinarily, the probiotic bacteria in the human gut form a dynamic community, their relative abundances shifting in response to diet, illness, and medication. This fluctuation, already ______ with broader ecological models of resilience and collapse, challenges researchers to rethink what constitutes a "healthy" microbiome.

Which choice completes the text so that it conforms to the conventions of Standard English?